Assumption #2. An adequate dose of colchicine(Drug information on colchicine) taken at the first signs of a gout attack can prevent a flare.
In a survey of patients who reported having one gout attack within the previous year, backed up by medical records review, colchicine protected against gout attacks only if it had been taken consistently over the preceding 14 days. Intermittent and inconsistent use of colchicine, or NSAIDs however consistently used, were ineffective in preventing gout attacks. (However, this community-based study cannot exclude the possibility that certain formulations and/or doses of NSAIDs, used consistently, may be effective.)
See: Effectiveness of Prophylaxis with Anti-Gout Medications On Risk of Gout Attacks
