Although NSAIDs are the most effective treatment for persons who experience the pain of osteoarthritis (OA), the risk of adverse effects with NSAIDs may outweigh the benefits in many older patients. The GI risk is well known; increased attention has been paid recently to the cardiovascular risk. The goals of OA management are pain reduction and improvement or preservation of mobility. A multidisciplinary approach to treatment is recommended.
Obesity is a modifiable risk factor for knee osteoarthritis (OA). Weight loss may reduce the risk of knee OA, and increased levels of physical activity may result in improvements in disability-related outcomes. However, intensity of physical activity is not as important in weight loss as total energy expended.
The CDC and the Arthritis Foundation (AF) are spearheading a new initiative designed to reduce the effect of osteoarthritis (OA) on Americans. In response to the recommendations outlined in this action plan, the AF also is cooperating with the Ad Council and the American College of Rheumatology in sponsoring a national public awareness campaign for OA management and prevention.
In patients with osteoarthritis (OA) who undergo joint replacement surgery, a greater perceived lack of control of arthritis symptoms negatively affects 1-year outcomes.
Walking with short, quick steps results in a small but significant increase in metabolic cost that may be beneficial for weight reduction or maintenance in obese persons and reduce the risk of knee osteoarthritis (OA), according to researchers at the Biomechanics and Energy Metabolism Laboratories, University of Massachusetts Amherst
Shoulder pain is a complex clinical condition, making the diagnosis difficult for even experienced clinicians. The most common causes of chronic shoulder pain are rotator cuff disorders and osteoarthritis of the glenohumeral joint. More »
Total shoulder arthroplasty (TSA) should not be performed in patients with glenohumeral osteoarthritis (GHOA) who have an irreparable rotator cuff tear, and physicians should use perioperative mechanical or chemical venous thromboembolism prophylaxis for patients who have undergone shoulder... More »
Close to three-fourths of women who have rheumatoid arthritis (RA) experience pain on a daily basis, even though three-fourths receive medication for pain relief, according to a new study presented at the 2010 Annual Congress of the European League Against Rheumatism (EULAR), held recently in Rome. More »
A 48–year–old woman was admitted to the division of rheumatology because of swelling and mild pain in her right knee. In the previous 3 months, she had experienced several episodes of locking of the knee; on palpation, the knee felt like a“bag of nuts.” On physical examination, hydrarthrosis and the... More »
(FO) in the treatment of knee and hiposteoarthritis. METHOD: The SOFMER (French Physical Medicine ... Evaluation (NAHAE). RESULTS: In medial kneeosteoarthritis foot pronation orthotics--when there are no contraindications--can ...
adherence to physical therapy programs by patients with hip or kneeosteoarthritis. METHODS: We used the method recommended by the French ... The relevance of widely used incentives in patients with hip or kneeosteoarthritis should be evaluated in new therapeutic trials. ...
Review New developments in osteoarthritis. Prevention of injury-related kneeosteoarthritis: opportunities for the primary and secondary prevention of kneeosteoarthritis... Where risk factors have been identified in knee and hiposteoarthritis (OA) with few exceptions no prevention strategies have proven beneficial. ...
determine independent associations with diet percentage body fat and kneeosteoarthritis severity. We also examined healthy porcine cartilage explants treated ... fat with a multivariate model revealed a significant association between kneeosteoarthritis severity and serum levels of leptin adiponectin and IL-1α ...
Prevention of injury-related kneeosteoarthritis: opportunities for the primary and secondary prevention of kneeosteoarthritis Charles R Ratzlaff ... data on knee joint injury as a major cause of osteoarthritis (OA) and promising developments in primary and secondary ...
osteoarthritis progression presumably by impaired load attenuation. How meniscal tears affect osteoarthritis is unclear; subregional examination may help ... Methods Participants with kneeosteoarthritis underwent bilateral knee MRI at baseline and 2 years. Mean cartilage thickness within each subregion was quantified. ...
DIO3) and Indian hedgehog were measured and associated with osteoarthritis in a meta-analyses in European populations from the UK The Netherlands Greece and Spain containing a total of 3252 osteoarthritis cases and 2132 controls. ...
Basic and translational research Extended report Superoxide dismutase downregulation in osteoarthritis progression and end-stage disease ... Oxidative stress is proposed as an important factor in osteoarthritis (OA). Objective To investigate the expression of the three ...
the bones as they move against each other. In spinal osteoarthritis the cartilage lining the facet joints (vertebral joints) ... disks between the vertebrae but is a separate medical condition. Osteoarthritis occurs as a person ages but is not a direct ...
Research article Relationship between patient-reported disease severity in osteoarthritis and self-reported pain function and work productivity Alesia B Sadosky ... Introduction Understanding the relationship between patient-reported osteoarthritis (OA) severity and other patient-reported outcomes in the real-world clinical ...
chondroitin sulphate their combination celecoxib or placebo taken to treat osteoarthritis of the knee: 2-year results from GAIT ...Kneeosteoarthritis (OA) is a major cause of pain and functional limitation in older adults yet longer-term studies ...
Basic and translational research Extended report Inhibition of bone resorption blunts osteoarthritis in mice with high bone remodelling Abderrahim ...Osteoarthritis (OA) is characterised by cartilage degradation and bone lesions. Subchondral bone may be involved in the pathogenesis ...
