Although NSAIDs are the most effective treatment for persons who experience the pain of osteoarthritis (OA), the risk of adverse effects with NSAIDs may outweigh the benefits in many older patients. The GI risk is well known; increased attention has been paid recently to the cardiovascular risk. The goals of OA management are pain reduction and improvement or preservation of mobility. A multidisciplinary approach to treatment is recommended.
Obesity is a modifiable risk factor for knee osteoarthritis (OA). Weight loss may reduce the risk of knee OA, and increased levels of physical activity may result in improvements in disability-related outcomes. However, intensity of physical activity is not as important in weight loss as total energy expended.
The CDC and the Arthritis Foundation (AF) are spearheading a new initiative designed to reduce the effect of osteoarthritis (OA) on Americans. In response to the recommendations outlined in this action plan, the AF also is cooperating with the Ad Council and the American College of Rheumatology in sponsoring a national public awareness campaign for OA management and prevention.
In patients with osteoarthritis (OA) who undergo joint replacement surgery, a greater perceived lack of control of arthritis symptoms negatively affects 1-year outcomes.
Walking with short, quick steps results in a small but significant increase in metabolic cost that may be beneficial for weight reduction or maintenance in obese persons and reduce the risk of knee osteoarthritis (OA), according to researchers at the Biomechanics and Energy Metabolism Laboratories, University of Massachusetts Amherst
Close to three-fourths of women who have rheumatoid arthritis (RA) experience pain on a daily basis, even though three-fourths receive medication for pain relief, according to a new study presented at the 2010 Annual Congress of the European League Against Rheumatism (EULAR), held recently in Rome. More »
A 48–year–old woman was admitted to the division of rheumatology because of swelling and mild pain in her right knee. In the previous 3 months, she had experienced several episodes of locking of the knee; on palpation, the knee felt like a“bag of nuts.” On physical examination, hydrarthrosis and the... More »
Constitutional alignment of the leg (varus or valgus knee or foot rotation) may be a significant factor in determining the development and distribution of knee osteoarthritis (OA) but not isolated hip OA. More »
Inflammatory arthritis includes a variety of diseases; the most common are rheumatoid arthritis, ankylosing spondylitis, and psoriatic arthritis. A large proportion of patients seen in most rheumatology practices have inflammatory arthritis; these patients also are seen in the primary care setting,... More »
After a trip to El Salvador, a woman experienced fever, malaise, and other symptoms. She had a history of a positive antinuclear antibodies test result, Raynaud phenomenon, and erythematous rash. The patient was hospitalized for pneumonia, and her symptoms persisted when she received antibiotics.... More »
topics that are of common concern when assessing people with osteoarthritis. Within each topic are a few suggested specific points worth assessing. ... the person has kneeosteoarthritis with a clear history of mechanical locking (not gelling 'giving way' or ...
Hip pain and mobility deficits--hiposteoarthritis: clinical practice guidelines linked to the International Classification ... crutches and walkers can be used in patients with hiposteoarthritis to improve function associated with weight-bearing activities. ...
line of treatment for relieving pain and improving physical functioning in osteoarthritis (Towheed et al. 2003; Jordan et al. ... B - In patients with kneeosteoarthritis who are symptomatic despite general measures and systemic therapies evidence supports short term ...
knee replacement (ie arthroplasty). Patients with symptomatic osteoarthritis of the knee are to be encouraged to participate ... Use of a free-floating interpositional device should not be considered for symptomatic unicompartmental osteoarthritis of the knee. Lateral heel wedges should not be ...
Basic and translational research Extended report Superoxide dismutase downregulation in osteoarthritis progression and end-stage disease ... Oxidative stress is proposed as an important factor in osteoarthritis (OA). Objective To investigate the expression of the three ...
the bones as they move against each other. In spinal osteoarthritis the cartilage lining the facet joints (vertebral joints) ... disks between the vertebrae but is a separate medical condition. Osteoarthritis occurs as a person ages but is not a direct ...
2010;69:1573-1574 doi:10.1136/ard.2009.123661 Letter Risk prediction for severe osteoarthritis Georg ...Osteoarthritis (OA) is one of the most frequent musculoskeletal diseases worldwide and is associated with a high burden ...
Basic and translational research Extended report Inhibition of bone resorption blunts osteoarthritis in mice with high bone remodelling Abderrahim ...Osteoarthritis (OA) is characterised by cartilage degradation and bone lesions. Subchondral bone may be involved in the pathogenesis ...
chondroitin sulphate their combination celecoxib or placebo taken to treat osteoarthritis of the knee: 2-year results from GAIT ...Kneeosteoarthritis (OA) is a major cause of pain and functional limitation in older adults yet longer-term studies ...
Extended report Assessment of gastrointestinal and cardiovascular risk in patients with osteoarthritis who require NSAIDs: the LOGICA study Angel Lanas1 ... Medical management of adults with osteoarthritis (OA) who require non-steroidal anti-inflammatory drugs (NSAIDs) ...
Relationship between bone marrow lesions cartilage loss and pain in kneeosteoarthritis: results from a randomised controlled clinical trial using MRI ... the effect of licofelone in comparison with naproxen on kneeosteoarthritis (OA) the presence of and change in bone ...
synovitis synovial thickening effusion and power Doppler signal (PDS)—with symptoms in hand osteoarthritis (HOA). ... assessed for pain upon palpation and filled in Australian/Canadian Osteoarthritis Index (AUSCAN) scores visual analogue scale pain ...
The association between radiographic kneeosteoarthritis and knee symptoms function and quality of life 10–15 years after anterior cruciate ligament reconstruction ... There are conflicting results in the literature regarding the association between radiographic kneeosteoarthritis (OA) and symptoms and function in subjects ...
The responsiveness of joint counts patient-reported measures and proposed composite scores in hand osteoarthritis: analyses from a placebo-controlled trial ... 28 and 42 days and included the Australian/Canadian osteoarthritis hand index (AUSCAN) visual analogue pain subscale ...
