RA and lymphoma risk: A critical link?
June 28, 2010
A history of cancer is not a major risk factor for rheumatoid arthritis (RA), but there is an increased lymphoma risk after RA diagnosis.
Current treatments are good medicine for children with Lyme arthritis
June 28, 2010
Children with Lyme arthritis have an excellent prognosis. Treatment of patients who have antibiotic-refractory Lyme arthritis with NSAIDs, intra-articular corticosteroid injections, or disease-modifying antirheumatic drugs (DMARDs) is safe and effective, with no evidence of chronic arthritis, permanent joint changes, or breakthrough cases of persistent infection.
RA trend reversal: Incidence on the rise in women
June 28, 2010
After a sharp decline in the incidence of rheumatoid arthritis (RA) over the previous 4 decades, it appears to have increased slightly in women in more recent years, along with an increase in prevalence.
RA carries “social costs” as well as economic burden
April 25, 2010
The deleterious effects of rheumatoid arthritis (RA) on employment and productivity are clearly associated with a burden on the US economy. However, RA also has significant “social costs” for both employed and unemployed persons.
Neuromuscular training puts a stop to lower limb injuries
April 25, 2010
Proprioceptive and neuromuscular training help reduce the incidence of some types of injuries among adolescent and young adult athletes participating in sports that involve pivoting. Balance exercises and multi-interventional training programs (balance plus strength and flexibility maneuvers) may be particularly effective in preventing basketball, soccer, handball, and floorball injuries.
Ankylosing spondylitis best identified with erosions on MRI
April 25, 2010
For patients who have ankylosing spondylitis (AS), radiographic assessment of the sacroiliac joint with MRI is the cornerstone of evaluation and treatment. Erosions alone—rather than bone marrow edema or contrast medium enhancement—are the most disease-specific measurable imaging findings in sacroiliac MRI of patients with AS in clinical practice.
Cardiovascular benefits with statins outweigh diabetes risk
April 25, 2010
There is a small absolute risk of diabetes mellitus (DM) in patients who receive statin therapy, but that risk is easily outweighed by the benefit that statins provide in reducing cardiovascular (CV) events. Therefore, clinical practice does not need to change for patients with moderate or high CV risk or existing CV disease.
Fracture prediction models are sex- and site-specific
April 6, 2010
Prediction of fractures is specific for the patient’s sex and the site of bone mineral density (BMD) measurement. This finding challenges the practice of using similar models—and of measuring BMD at the hip only—to predict fracture risk for men and for women.
Vitamin D deficiency linked with osteoarthritis in older men
April 6, 2010
There is a high prevalence of 25-hydroxyvitamin D (25[OH]D) deficiency in older men who have radiographic hip osteoarthritis (OA). Because 25(OH)D plays a significant role in bone and cartilage maintenance, therapeutic interventions with vitamin D are warranted to augment their skeletal health.
Caution: MRI has low specificity for RA
April 6, 2010
MRI abnormalities that resemble rheumatoid arthritis (RA) pathologies often are found in the metacarpophalangeal and wrist joints of healthy persons. Although MRI is highly sensitive for tracking the progression of erosions, it has low specificity for RA, suggesting caution in the interpretation of joint lesions on MRI, especially in early arthritis.
Comorbidity patterns vary with rheumatologic disease
April 6, 2010
Separate patterns of comorbidity are identified in patients who have fibromyalgia syndrome (FMS), systemic lupus erythematosus (SLE), rheumatoid arthritis (RA), and noninflammatory rheumatic disorders (NIRD). The patterns include the type of comorbid variables reported and their associations with age and disease duration.
Scleroderma “SOS”: Telangiectases a biomarker for pulmonary disease
March 2, 2010
There are significant associations between the increased numbers of telangiectases in patients with scleroderma and the presence of pulmonary arterial hypertension (PAH). Cutaneous telangiectases may be a manifestation of the vasculopathy of scleroderma that could serve as a clinical biomarker for pulmonary vascular disease.
Prevention pays off in girls who play soccer
March 2, 2010
For girls who play soccer, participation in a multifaceted injury prevention program that combines education, proper motion patterns, strength, and balance may reduce the incidence of acute knee injuries significantly. It also may lessen the severity of injuries that do occur.
Obesity trend may be thinning out
March 2, 2010
The prevalence of obesity in the United States remains high, exceeding 30% in most sex and age groups. However, the prevalence may not be continuing at as high a level as in earlier periods, especially in women and perhaps in men.
Exercise helps improve sleep in chronic fatigue syndrome
March 2, 2010
Although sleep often is disturbed in persons with chronic fatigue syndrome (CFS), activity-related exacerbation of symptoms is not related to poor sleep. In fact, persons with CFS often sleep better after engaging in exercise.
Is late-onset lupus a “wolf in sheep's clothing”?
March 2, 2010
Late-onset systemic lupus erythematosus (SLE), often considered to have a benign disease course, actually involves greater disease activity and comorbidities than early-onset SLE. Differences in disease activity may be associated with an interaction between the SLE and age.