Practice Guidelines

National Guideline Clearinghouse | Guidelines by Topic: Lupus Erythematosus, Systemic

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National Guideline Clearinghouse | Guidelines by Topic: Lupus Erythematosus, Cutaneous

www.guidelines.gov -

National Guideline Clearinghouse | Systemic lupus erythematosus (SLE).

www.guidelines.gov -

National Guideline Clearinghouse | American College of Rheumatology guidelines for screening, treatment, and management of lupus nephritis.

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Lupus

LATEST ARTICLES

Showing 1 - 7 of 73 results.

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JOURNAL SCAN

CD247 variants and single-nucleotide polymorphisms observed in systemic lupus erythematosus patients

rheumatology.oxfordjournals.org - 3/22/13

SLE is associated with a deficiency in cluster of differentiation 247 (CD247, also known as CD3 zeta chain), a component of the T-cell receptor (TCR)–CD3 complex. A comprehensive analysis showed that in more than half of SLE patients tested CD247 expression was either attenuated or absent. Recent evidence suggests that these variations in expression profiles may be due, at least in part, to polymorphisms in the CD247 gene. Aberrant CD247 transcript variants displaying either spliced

Improvements in health-related quality of life with belimumab, a B-lymphocyte stimulator-specific inhibitor, in patients with autoantibody-positive systemic lupus erythematosus from the randomised controlled BLISS trials

ard.bmj.com - 3/22/13

Objective

Assess the effects of belimumab treatment plus standard systemic lupus erythematosus (SLE) therapy on health-related quality of life (HRQOL) in patients with active, autoantibody-positive SLE.

Methods

Patients received standard therapy plus placebo or belimumab 1 or 10 mg/kg in two multicentre, randomised controlled trials of 52 (BLISS-52; N=865) and 76 (BLISS-76; N=819) weeks’ duration. Responders were evaluated by SLE Responder Index at week

A case of systemic lupus erythematosus with bamboo joint-like corditis as an antecedent symptom

rheumatology.oxfordjournals.org - 3/19/13

Comparison of the psychometric properties of health-related quality of life measures used in adults with systemic lupus erythematosus: a review of the literature

rheumatology.oxfordjournals.org - 3/19/13

Objective. A review of the literature was undertaken to evaluate the development and psychometric properties of health-related quality of life (HRQoL) measures used in adults with SLE. This information will help clinicians make an informed choice about the measures most appropriate for research and clinical practice.

Methods. Using the key words lupus and quality of life, full original papers in English were identified from six databases: OVID MEDLINE, EMBASE, Allied and Complemen

Protective autoantibodies in the rheumatic diseases: lessons for therapy

feeds.nature.com - 3/19/13

Pathogenic IgG autoantibodies have established roles in diseases including systemic lupus erythematosus and rheumatoid arthritis. Less familiar are the influences of naturally arising IgM autoantibodies, which enhance phagocytic clearance of apoptotic cells and have the capacity to block inflammatory responses induced by Toll-like receptor ligands and autoantibody-containing immune complexes. Intriguing data from animal models and clinical studies, suggesting that it might become possible to exploit these

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CLINICAL TRIALS

Triptorelin for Ovary Protection in Childhood Onset Lupus

www.clinicaltrials.gov -

Triptorelin for Ovary Protection in Childhood Onset Lupus. This study is currently recruiting participants.

Monoclonal Antibody Treatment for Systemic Lupus Erythematosus

www.clinicaltrials.gov -

Monoclonal Antibody Treatment for Systemic Lupus Erythematosus. This study has been completed.

Study of Epratuzumab in Systemic Lupus Erythematosus

www.clinicaltrials.gov -

Study of Epratuzumab in Systemic Lupus Erythematosus. This study has been terminated.

Treating Systemic Lupus Erythematosus (SLE) Patients With CTLA4-IgG4m (RG2077)

www.clinicaltrials.gov -

Treating Systemic Lupus Erythematosus ( SLE) Patients With CTLA4-IgG4m ( RG2077).

Atherosclerosis Prevention in Pediatric Lupus Erythematosus (APPLE)

www.clinicaltrials.gov -

Atherosclerosis Prevention in Pediatric Lupus Erythematosus ( APPLE). This study is ongoing, but not recruiting participants.

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TOPIC INDEX

FROM PHYSICIANS PRACTICE

Five Steps to Improving Patient Access
Judy Capko, May 21, 2013
Patient access is getting increased attention through reform initiatives. Here are five steps you can take to make sure patients get appropriate access to care in your office.

Growing HIPAA Threat – Ignore Windows XP at Your Own Peril
Marion K. Jenkins, May 21, 2013
Chances are good that you have some major ticking software time bombs lurking in your medical practice's computer environment, namely Windows XP and Server 2003.

Finding Physician Work-Life Balance in the Small Moments
Jennifer Frank, MD, May 21, 2013
At my practice and at home, things are always busy. There's laundry or homework, or a patient with needs.

Three Areas to Reduce Costs at Your Medical Practice
Greg Mertz, May 19, 2013
By taking a hard look at reducing costs for staffing, overhead, and technology at your medical practice, you may see increased physician compensation.

Dos and Don’ts for Starting a Physician Blog
Michael Woo-Ming, MD, May 18, 2013
Starting a physician blog can provide your medical practice with marketing benefits, but it's important to do it right.