A 65-year-old man, who was lost to follow-up after abdominal-perineal resection for rectal adenocarcinoma 9 months earlier, presents with progressively worsening neurological symptoms, including bilateral hearing loss, dizziness, gait disturbance, ataxia, and blindness in the right eye. More »
After a trip to El Salvador, a woman experienced fever, malaise, and other symptoms. She had a history of a positive antinuclear antibodies test result, Raynaud phenomenon, and erythematous rash. The patient was hospitalized for pneumonia, and her symptoms persisted when she received antibiotics.... More »
An educational initiative aimed at eliminating ethnic and racial disparities in the diagnosis and management of lupus was launched recently by the American College of Rheumatology (ACR) in conjunction with the US Department of Health and Human Services' Office of Minority Health, Office on Women’s... More »
For the past 7 years, a 32-year-old African-American man had multiple nonpruritic scalp abscesses. He also reported intermittent fever and joint pain. The... More »
A 45-year-old man presents with a 4- to 5-year history of an intermittent, asymptomatic, red, circular rash on his trunk. Trials of antifungal creams have... More »
A 4-year-old boy with a history of autism presents to his pediatrician’s office with a complaint of right leg pain. He is presumed to have pulled a muscle; an elastic bandage is applied and he is given ibuprofen. Over the next few days, he begins falling and tripping and is unable to maintain his... More »
Most children who present with undifferentiated rash and fever—or fever and rash and nonspecific physical findings—have a benign viral illness. However, identifying those few who have an early or atypical presentation of a more serious disease is vitally important. Here—clues that can help. More »
Separate patterns of comorbidity are identified in patients who have fibromyalgia syndrome (FMS), systemic lupus erythematosus (SLE), rheumatoid arthritis (RA), and noninflammatory rheumatic disorders (NIRD). The patterns include the type of comorbid variables reported and their associations with... More »
The incidence rates of non-Hodgkin lymphoma (NHL) in the United States have almost doubled between 1970 and 1990, representing one of the largest increases of any cancer. Although the overall incidence rates of NHL began to stabilize in the late 1990s, the temporal trends varied by histologic... More »
For the past 7 years, a 32-year-old African-American man had multiple nonpruritic scalp abscesses. He also reported intermittent fever and joint pain. The... 
A 45-year-old man presents with a 4- to 5-year history of an intermittent, asymptomatic, red, circular rash on his trunk. Trials of antifungal creams have... 
A 56-year-old woman seen during physician’s hospice visit. Stormy course from lupus nephritis, dialysisdependency, repeated episodes of... 