New Tools to Measure Disease Activity in SLE
December 3, 2013
ACR2013: Well adapted to electronic formats, the new Lupus Activity Scoring Tool stands up well to other disease activity indices. Also, an online toolkit of validated lupus assessment tools.
Physical Signs of Meniscal Tear: Red Herrings in All But the Young
November 15, 2013
(VIDEO) Another dictum from medical school gives way to medical research: Clicking, popping, and locking are not useful for diagnosis and prognosis of suspected meniscal tear in patients over 45. Harvard's Dr. Jeffrey Katz reveals signs that actually are informative in this age group.
What Can You Do to Prevent Lupus Damage?
November 14, 2013
(VIDEO) Data from an international lupus cohort shows the factors that correlate with permanent damage to renal, pulmonary, and other body systems. Some of them are modifiable.
SLE and Primary Sjӧgren’s – Erosive Diseases?
November 13, 2013
ACR2013: Joints erode in systemic lupus erythematosus and primary Sjӧgren’s Syndrome. But French researchers say their MRI studies don't justify classing them as erosive disorders like rheumatoid arthritis.
When Does The RA "Window of Opportunity" Actually Open?
November 13, 2013
(VIDEO) Researchers in Norway used data from an observational study of patients with swollen joints to see how many with early signs of rheumatoid arthritis recovered without any treatment at all, and how quickly.
Biologics May Cut Heart Risk in RA
November 11, 2013
ACR2013: A prospective study of more than 200 patients showed that biologic therapy lowered their cardiovascular disease risk by almost 12% over two years.
JAK Inhibitors 2013 – A Progress Report
November 11, 2013
ACR 2013: Latest results from continuing trials of the tofacitinib show the most effective dosages for RA, good news about safety, but a warning about an age difference.
Autism and ADHD Risk Increased for SLE Offspring
November 1, 2013
ACR2013: As well as neonatal lupus and heart block, new research suggests that children born to women with lupus may face higher risks for autism and attention deficit hyperactivity disorder.
Can Triple Therapy Match Biologics For RA At Lower Cost?
October 30, 2013
ACR 2013: Debates about drug costs in rheumatoid arthritis dominated discussions at ACR this year, and one session was formally billed a debate. Will less-costly triple therapy someday be mandated for early RA?
New PDE4 Inhibitor Conquers PsA in Phase 3 Trial
October 28, 2013
ACR2013: Apremilast, a new kind of anti-inflammatory, proved significantly better than placebo against psoriatic arthritis after 52 weeks. Adverse effects were short-lived. Results for ustekinumab also held up after a year.
Study Finds Symptom Patterns Common to "Pre-RA"
October 27, 2013
ACR2013: What clues suggest impending rheumatoid arthritis in a patient with stiffness and joint problems? A comparative study offers an answer, and another suggests that sleep problems are an important clue to severity of RA.
Six New Insights About RA Treament from the AMPLE Trial
June 20, 2013
EULAR 2013: Two-year data from a head-to-head comparison of abatacept and adalimumab show them comparably effective for rheumatoid arthritis. But the former is less costly with fewer noteworthy adverse effects.
Macrophages and CD4+ T Cells Found Lurking in Arthritic Knees
May 1, 2013
Synovitis is present in 90% of painful knees, and emerging data is showing that this inflammation is "not just a bystander" in osteoarthritis-induced damage. Research is revealing the roles of macrophages and T-cells, and signposts toward new drug targets.
Five Small Steps Toward New Drug Options for OA
April 25, 2013
No speaker at the OARSI meeting turned up with the Holy Grail -- a new disease modifying osteoarthritis drug (DMOAD). Some promising alternatives are not available to US patients; others are in very preliminary testing.
Exercise and Knee OA: Five Things We Know (And Some We Do Not)
April 24, 2013
Patients with knee osteoarthritis should have mild exercise every day to reduce inflammation, should walk with shorter steps to reduce knee loading, and should strengthen their upper leg muscles, to judge from new research. But studies have yet to say how much exercise is best, how often, and at what intensity.
Why No News is Good News in Imaging Knee OA
April 23, 2013
What you want to see in progressive images of knee osteoarthritis is not a particular kind of change, but homeostasis, to judge from two studies presented at the annual meeting of OARSI.
Chondroitin Sulfate Use Linked to Reduced Need for Knee Replacement
April 20, 2013
More support for the supplement chondroitin sulfate (CS) in osteoarthritis: In a large observational study from Spain, six months' use of CS significantly reduced the likelihood of having total knee replacement. But observers at the OARSI meeting noted the well-known issues in applying this to US patients.
AAOS: Most With Massive Rotator Cuff Tears Can Avoid Surgery
March 19, 2013
Conservative methods are good enough for 75% of patients with major rotator cuff tears, according to a single-center study reported at AAOS. As to those with shoulder arthritis, results of surgery are very good but not permanent.
Osteoarthritis as a Chronic Wound
March 26, 2013
(AUDIO) Intensive analysis of protein pathways inside joints is showing strong activity among messengers involved in wound healing. In this podcast, learn about the new research that backs the vision of arthritis as a chronic wound, and the implications for management.
Good News About Belimumab and SLE
November 6, 2012
Updates to be presented at the American College of Radiology meeting begin to resolve some outstanding questions about the breakthrough drug for treatment of systemic lupus erythematosus.
The Importance of Ultrasound in Choosing RA Treatment
November 11, 2012
(VIDEO) Ultrasound can trump the DAS28 in weighing rheumatoid arthritis symptoms and joint signs when making treatment decisions, says James Dale MD, who describes his study reported at the American College of Rheumatology meeting.
Previous articles from Musculoskeletal Network and the Journal of Musculoskeletal Medicine are available in the online archive.
For previous articles on a particular topic, click the Search box at the upper right of the screen. You can optimize your search for either relevance or date.