The Journal of Musculoskeletal Medicine en Copyright 2009, CMPMedica US Sat, 25 May 2013 13:00:01 GMT Sat, 25 May 2013 13:00:01 GMT http://blogs.law.harvard.edu/tech/rss http://www.musculoskeletalnetwork.com/women/content/article/1145622/2144032?CID=rss Women with persistent antiphospholipid antibodies (aPLs) apparently have pregnancy outcomes similar to those of women under treatment for antiphospholipid syndrome (APS) and even comparable to unmatched controls. Fri, 24 May 2013 12:00:00 GMT http://www.musculoskeletalnetwork.com/pain/content/article/1145622/2144107?CID=rss <img width="80" height="100" src="http://imaging.cmpmedica.com/shared/zone5/0810JMMDAMF1.jpg" alt="" border="0" align="left" style="padding-right:5px;" />Like so many inflammatory conditions, complex regional pain syndrome (yes, there's growing evidence it's inflammatory) demands early treatment. Yet it is devilishly difficult to recognize its initial stages. Here are the signs, and an algorithm for management.<br style="clear:both;"/> Thu, 23 May 2013 12:00:00 GMT http://www.musculoskeletalnetwork.com/display/article/1145622/2143382?CID=rss Sandoz has announced a voluntary recall of two lots of its injectable methotrexate sodium, after finding particulates in vials during a routine quality examination. Wed, 22 May 2013 12:00:00 GMT http://www.musculoskeletalnetwork.com/osteoarthritis/content/article/1145622/2143336?CID=rss Collaborating to reassess patient-level data from existing trials, a new cooperative effort is working to improve the evidence base for osteoarthritis treatments. Tue, 21 May 2013 12:00:00 GMT http://www.musculoskeletalnetwork.com/rheumatoid-arthritis/content/article/1145622/2143134?CID=rss <img width="80" height="110" src=http://www.musculoskeletalnetwork.com/image/image_gallery?img_id=2143146&t=1369083431989" alt="" border="0" align="left" style="padding-right:5px;" />The past decade has seen remarkable advances in our understanding of rheumatoid arthritis. However, challenges remain. Resolving them offers hope for even greater success in the future.<br style="clear:both;"/> Mon, 20 May 2013 12:00:00 GMT http://www.musculoskeletalnetwork.com/rheumatic-diseases/content/article/1145622/2143101?CID=rss New in the nonspecialty journals: A new option for patients with autoimmune disease and HCV infection. The value of combined therapy for osteoporosis. Prognosis predictors for chronic pain, a new opioid adverse effect, and more ... Mon, 20 May 2013 12:00:00 GMT http://www.musculoskeletalnetwork.com/skin-diseases/content/article/1145622/2142974?CID=rss <img width="100" height="80" src="http://www.consultantlive.com/image/image_gallery?img_id=1387374" alt="" border="0" align="left" style="padding-right:5px;" />Is it a form of lupus, myositis, or a drug reaction? Check your knowledge of skin eruptions and the associated rheumatologic conditions in this brief photo essay.<br style="clear:both;"/> Fri, 17 May 2013 12:00:00 GMT http://www.musculoskeletalnetwork.com/display/article/1145622/2142812?CID=rss The FDA has approved the tumor necrosis factor (TNF) blocker golimumab (Simponi) for treatment of moderate to severe ulcerative colitis in adults. This is the first non-arthritis indication for the biologic, which is already approved for rheumatoid arthritis, psoriatic arthritis, and ankylosing spondylitis. Thu, 16 May 2013 12:00:00 GMT http://www.musculoskeletalnetwork.com/gout/content/article/1145622/2142734?CID=rss They may be supported by guidelines and commonly used in practice, but joint injections with glucocorticoids for acute gout are not backed by any randomized controlled clinical trials, according to a new Cochrane report. However, the report backs away from saying they should not be used. Wed, 15 May 2013 12:00:00 GMT http://www.musculoskeletalnetwork.com/rheumatic-diseases/content/article/1145622/2142468?CID=rss A small, randomized clinical trial from Germany suggests that two weeks of high-dose oral prednisone produces a clinically relevant response in patients with active ankylyosing spondylitis (AS) refractory to NSAIDs. Tue, 14 May 2013 12:00:00 GMT http://www.musculoskeletalnetwork.com/rheumatic-diseases/content/article/1145622/2142411?CID=rss New in the non-rheumatology journals, much about pain: A review based on 2012 fibromyalgia guidelines from Canada, a viewpoint on safe use of opioids, the evidence to back spinal pain interventions. Also: fast-track arthroplasty, and more newfound genes. Mon, 13 May 2013 12:00:00 GMT http://www.musculoskeletalnetwork.com/juvenile-arthritis/content/article/1145622/2141822?CID=rss The FDA has approved canakinumab (Ilaris) for treatment of active systemic juvenile idiopathic arthritis) in patients aged 2 years and older. The drug is administered monthly by subcutaneous injection. Fri, 10 May 2013 12:00:00 GMT http://www.musculoskeletalnetwork.com/rheumatoid-arthritis/content/article/1145622/2141462?CID=rss In a comprehensive review of clinical trials, combination therapies with biologics offered better chances of long-term remission than monotherapy with a DMARD. Wed, 8 May 2013 12:00:00 GMT http://www.musculoskeletalnetwork.com/rheumatic-diseases/content/article/1145622/2141440?CID=rss New in the non-rheumatology journals: Adverse effects of TNF-α inhibitors, a comment on meniscectomy vs. physical therapy, and the latest on adolescent scoliosis. Tue, 7 May 2013 12:00:00 GMT http://www.musculoskeletalnetwork.com/rheumatoid-arthritis/content/article/1145622/2140798?CID=rss Quest Diagnostics says the biomarker 14-3-3eta in its new test greatly improves sensitivity in detecting early rheumatoid arthritis. But the data is not yet published. Fri, 3 May 2013 12:00:00 GMT http://www.musculoskeletalnetwork.com/osteoarthritis/content/article/1145622/2140555?CID=rss New research has examined 3D motion and muscle activity in knee osteoarthritis, and correlated gait with pain. Result: a better description of knees destined for replacement. Thu, 2 May 2013 12:00:00 GMT http://www.musculoskeletalnetwork.com/rheumatic-diseases/content/article/1145622/2140536?CID=rss <img width="110" height="75" src="http://imaging.cmpmedica.com/shared/zone5/0809JMMIMDF1.jpg" alt="" border="0" align="left" style="padding-right:5px;" />A 39-year-old woman, in her eighth week of pregnancy, experienced aching pain that worsened with activity. Weakness and fatigue set in three days later in her thigh and proximal arm muscle. Then a mildly pruritic rash developed across the forehead, nose, and forearms.<br style="clear:both;"/> Wed, 1 May 2013 12:00:00 GMT http://www.musculoskeletalnetwork.com/osteoarthritis/content/article/1145622/2140524?CID=rss Synovitis is present in 90% of painful knees, and emerging data is showing that this inflammation is "not just a bystander" in osteoarthritis-induced damage. Research is revealing the roles of macrophages and T-cells, and signposts toward new drug targets. Wed, 1 May 2013 12:00:00 GMT